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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 1
2009 3
2010 2
2011 1
2012 3
2013 4
2014 2
2016 3
2017 1
2019 1
2022 2
2023 1
2024 0

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23 results

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Page 1
Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine.
Kavanagh ME, Horning BD, Khattri R, Roy N, Lu JP, Whitby LR, Ye E, Brannon JC, Parker A, Chick JM, Eissler CL, Wong AJ, Rodriguez JL, Rodiles S, Masuda K, Teijaro JR, Simon GM, Patricelli MP, Cravatt BF. Kavanagh ME, et al. Among authors: whitby lr. Nat Chem Biol. 2022 Dec;18(12):1388-1398. doi: 10.1038/s41589-022-01098-0. Epub 2022 Sep 12. Nat Chem Biol. 2022. PMID: 36097295 Free PMC article.
Proteomic discovery of chemical probes that perturb protein complexes in human cells.
Lazear MR, Remsberg JR, Jaeger MG, Rothamel K, Her HL, DeMeester KE, Njomen E, Hogg SJ, Rahman J, Whitby LR, Won SJ, Schafroth MA, Ogasawara D, Yokoyama M, Lindsey GL, Li H, Germain J, Barbas S, Vaughan J, Hanigan TW, Vartabedian VF, Reinhardt CJ, Dix MM, Koo SJ, Heo I, Teijaro JR, Simon GM, Ghosh B, Abdel-Wahab O, Ahn K, Saghatelian A, Melillo B, Schreiber SL, Yeo GW, Cravatt BF. Lazear MR, et al. Among authors: whitby lr. Mol Cell. 2023 May 18;83(10):1725-1742.e12. doi: 10.1016/j.molcel.2023.03.026. Epub 2023 Apr 20. Mol Cell. 2023. PMID: 37084731
SAR studies of 4-acyl-1,6-dialkylpiperazin-2-one arenavirus cell entry inhibitors.
Plewe MB, Whitby LR, Naik S, Brown ER, Sokolova NV, Gantla VR, York J, Nunberg JH, Zhang L, Kalveram B, Freiberg AN, Boger DL, Henkel G, McCormack K. Plewe MB, et al. Among authors: whitby lr. Bioorg Med Chem Lett. 2019 Nov 15;29(22):126620. doi: 10.1016/j.bmcl.2019.08.024. Epub 2019 Aug 24. Bioorg Med Chem Lett. 2019. PMID: 31537423 Free PMC article.
Author Correction: Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine.
Kavanagh ME, Horning BD, Khattri R, Roy N, Lu JP, Whitby LR, Ye E, Brannon JC, Parker A, Chick JM, Eissler CL, Wong AJ, Rodriguez JL, Rodiles S, Masuda K, Teijaro JR, Simon GM, Patricelli MP, Cravatt BF. Kavanagh ME, et al. Among authors: whitby lr. Nat Chem Biol. 2022 Nov;18(11):1288. doi: 10.1038/s41589-022-01181-6. Nat Chem Biol. 2022. PMID: 36180594 No abstract available.
TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Wang Y, Su L, Morin MD, Jones BT, Whitby LR, Surakattula MM, Huang H, Shi H, Choi JH, Wang KW, Moresco EM, Berger M, Zhan X, Zhang H, Boger DL, Beutler B. Wang Y, et al. Among authors: whitby lr. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):E884-93. doi: 10.1073/pnas.1525639113. Epub 2016 Feb 1. Proc Natl Acad Sci U S A. 2016. PMID: 26831104 Free PMC article.
Selective inhibitors and tailored activity probes for lipoprotein-associated phospholipase A(2).
Nagano JM, Hsu KL, Whitby LR, Niphakis MJ, Speers AE, Brown SJ, Spicer T, Fernandez-Vega V, Ferguson J, Hodder P, Srinivasan P, Gonzalez TD, Rosen H, Bahnson BJ, Cravatt BF. Nagano JM, et al. Among authors: whitby lr. Bioorg Med Chem Lett. 2013 Feb 1;23(3):839-43. doi: 10.1016/j.bmcl.2012.11.061. Epub 2012 Dec 2. Bioorg Med Chem Lett. 2013. PMID: 23260346 Free PMC article.
23 results